Guillermina Estiú

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Alassane Mbengue, Souvik Bhattacharjee, Trupti Pandharkar et al. · Nature · 2015 · 608 citations

Medicine, Molecular Biology, Pharmacology +16

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Wenyu Yu, Emma J. Chory, Amy K. Wernimont et al. · Nature Communications · 2012 · 286 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma

Teru Hideshima, Jun Qi, Ronald M. Paranal et al. · Proceedings of the National Academy of Sciences · 2016 · 139 citations · Full text

Medicine, Oncology, Pharmacology +13

Blueprint for antimicrobial hit discovery targeting metabolic networks

Yihui Shen, J. Liu, Guillermina Estiú et al. · Proceedings of the National Academy of Sciences · 2010 · 110 citations · Full text

Life Sciences, Bioinformatics, Systems Biology +17

Structural Origin of Selectivity in Class II-Selective Histone Deacetylase Inhibitors

Guillermina Estiú, Edward F. Greenberg, Christopher B. Harrison et al. · Journal of Medicinal Chemistry · 2008 · 110 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14