X Y Li

Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo. Direct evidence for a pathogenetic role of the hydroxyl radical in myocardial stunning.

Jun Sun, Harsimran Kaur, Barry Halliwell et al. · Circulation Research · 1993 · 126 citations · Full text

Myocardial Ischemia, Lipid Peroxidation, Cardiovascular Pharmacology +18

Recurrent ischemia in the canine heart causes recurrent bursts of free radical production that have a cumulative effect on contractile function. A pathophysiological basis for chronic myocardial "stunning".

Roberto Bolli, Marcel Zughaib, X Y Li et al. · Journal of Clinical Investigation · 1995 · 123 citations · Full text

Repetitive Ischemia, Free Radical Production, Recurrent Oxidative Stress +16

Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs.

X Y Li, Paul B. McCay, Marcel Zughaib et al. · Journal of Clinical Investigation · 1993 · 110 citations · Full text

Cardiac Muscle, Conscious Dog, Oxidative Stress +20

Postischemic myocardial "stunning". Identification of major differences between the open-chest and the conscious dog and evaluation of the oxygen radical hypothesis in the conscious dog.

J F Triana, X Y Li, U Jamaluddin et al. · Circulation Research · 1991 · 107 citations · Full text

Heart Failure, Cardiovascular Toxicity, Conscious Dog +21

Direct evidence that the hydroxyl radical plays a pathogenetic role in myocardial "stunning" in the conscious dog and demonstration that stunning can be markedly attenuated without subsequent adverse effects.

Selim Sekili, Paul B. McCay, X Y Li et al. · Circulation Research · 1993 · 95 citations

Heart Failure, Antioxidant Therapy, Cardiovascular Toxicity +18