Marcel Zughaib

Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial

JoAnn Lindenfeld, Michael R. Zile, Akshay S. Desai et al. · The Lancet · 2021 · 391 citations

Heart Failure, Device Therapy, Cardiovascular Disease +6

Recurrent ischemia in the canine heart causes recurrent bursts of free radical production that have a cumulative effect on contractile function. A pathophysiological basis for chronic myocardial "stunning".

Roberto Bolli, Marcel Zughaib, X Y Li et al. · Journal of Clinical Investigation · 1995 · 123 citations · Full text

Repetitive Ischemia, Free Radical Production, Recurrent Oxidative Stress +16

Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs.

X Y Li, Paul B. McCay, Marcel Zughaib et al. · Journal of Clinical Investigation · 1993 · 110 citations · Full text

Cardiac Muscle, Conscious Dog, Oxidative Stress +20

Direct evidence that the hydroxyl radical plays a pathogenetic role in myocardial "stunning" in the conscious dog and demonstration that stunning can be markedly attenuated without subsequent adverse effects.

Selim Sekili, Paul B. McCay, X Y Li et al. · Circulation Research · 1993 · 95 citations

Heart Failure, Antioxidant Therapy, Cardiovascular Toxicity +18

The Relative Safety and Efficacy of Abciximab and Eptifibatide in Patients Undergoing Primary Percutaneous Coronary Intervention

Hitinder S. Gurm, Dean E. Smith, John Collins et al. · Journal of the American College of Cardiology · 2008 · 93 citations

Thrombosis, Percutaneous Coronary Intervention, Cardiovascular Disease +11