Sergio A. Alonso de Diego

1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads

Frederik Rombouts, Gary Tresadern, Óscar Delgado et al. · Journal of Medicinal Chemistry · 2015 · 76 citations · Full text

Pharmacotherapy, Hit Generation, Pharmaceutical Chemistry +21

Imidazo[1,2-<i>a</i>]pyridines: Orally Active Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

Andrés A. Trabanco, Gary Tresadern, Gregor J. Macdonald et al. · Journal of Medicinal Chemistry · 2012 · 60 citations · Full text

Pharmacotherapy, Molecular Pharmacology, Medicinal Chemistry +17

Efficient Synthesis of Enantiomerically Pure α-Alkyl Cyclopropanecarbonitrile Derivatives from Pyrazolines

J.L.G. Ruano, Sergio A. Alonso de Diego, Michel Martin et al. · Organic Letters · 2004 · 44 citations

Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads

Daniel Oehlrich, Aldo Peschiulli, Gary Tresadern et al. · ACS Medicinal Chemistry Letters · 2019 · 33 citations · Full text

(<i>Z</i>)-3-<i>p</i>-Tolylsulfinylacrylonitriles as Chiral Dipolarophiles:  Reactions with Diazoalkanes

J.L.G. Ruano, Sergio A. Alonso de Diego, Daniel Blanco‐Ania et al. · Organic Letters · 2001 · 31 citations

Derivatives, Heterocyclic, Biochemistry +13