Graham A. Tynan

Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

Inna S. Afonina, Graham A. Tynan, Susan E. Logue et al. · Molecular Cell · 2011 · 278 citations · Full text

Inflammation, Cytokine, Proinflammatory Activity +9

Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells

Sean P. Cullen, Conor M. Henry, Conor J. Kearney et al. · Molecular Cell · 2013 · 221 citations · Full text

Fas/cd95-induced Chemokines, Signal Transduction, Signaling Pathway +8

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production

Conor J. Kearney, Sean P. Cullen, Graham A. Tynan et al. · Cell Death and Differentiation · 2015 · 131 citations · Full text

Inflammation, Cytokine, Autoimmune Disease +11

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling

Clíona Ní Cheallaigh, Frederick J. Sheedy, James Harris et al. · Immunity · 2016 · 57 citations · Full text

Endogenous Oils Derived From Human Adipocytes Are Potent Adjuvants That Promote IL-1α–Dependent Inflammation

Graham A. Tynan, Claire H. Hearnden, Ewa Oleszycka et al. · Diabetes · 2014 · 46 citations · Full text

Lung Inflammation, Immunology, Immune Regulation +21