Neal W. Sach - Concepedia

Author

Neal W. Sach

Pfizer (United States)ORCID

Also Known As

N. W. Sach, Neal Sach, Neal W. Sach, Neal W. Sach, Sach, N., Sach, N.W., Sach, Neal, Sach, Neal W.

126

Publications

5.2K

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)Scripps Research Institute Pfizer (United Kingdom)Fleet Science Center University of Alberta

About

Neal W. Sach is an author at Pfizer (United States) specializing in organic chemistry, engineering, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Engineering	14	15	673
2	Natural Sciences	14	15	1.2K
3	Medicine	11	11	561
4	Biochemistry	7	7	775
5	Applied Physics	1	1	93

Neal W. Sach

Publications

Citations

H-Index

Page 1

	Year	Citations
Practical and innate carbon–hydrogen functionalization of heterocycles Yuta Fujiwara, Janice A. Dixon, Fionn O’Hara, Nature Organic ChemistryOrganometallic CatalysisCarbon–hydrogen FunctionalizationChemistry	2012	910
Discovery of (10 <i>R</i> )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- <i>2H</i> -8,4-(metheno)pyrazolo[4,3- <i>h</i> ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations Ted W. Johnson, Paul Richardson, Simon Bailey, Journal of Medicinal Chemistry	2014	571
Strain-release amination Ryan Gianatassio, Justin M. Lopchuk, Jie Wang, Science Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryDrug CandidatesBiochemistry	2016	546
A platform for automated nanomole-scale reaction screening and micromole-scale synthesis in flow Damith Perera, Joseph W. Tucker, Shalini Brahmbhatt, Science	2018	478
Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications Yu Kawamata, Julien C. Vantourout, David P. Hickey, Journal of the American Chemical Society	2019	345
Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity Justin M. Lopchuk, Kasper Fjelbye, Yu Kawamata, Journal of the American Chemical Society	2017	326
Visible‐Light‐Initiated Manganese Catalysis for C−H Alkylation of Heteroarenes: Applications and Mechanistic Studies Philippe Nuhant, Martins S. Oderinde, Julien Genovino, Angewandte Chemie International Edition	2017	182
The Use of Copper Flow Reactor Technology for the Continuous Synthesis of 1,4‐Disubstituted 1,2,3‐Triazoles Andrew R. Bogdan, Neal W. Sach Advanced Synthesis & Catalysis Continuous SynthesisNovel OrganocatalystsEngineeringOrganic AzidesContinuous Flow Process	2009	159
Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (<i>R</i>)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2<i>H</i>)-one (PF-06821497) Pei‐Pei Kung, Patrick Bingham, Alexei Brooun, Journal of Medicinal Chemistry	2017	125
Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib Qinhua Huang, Ted W. Johnson, Simon Bailey, Journal of Medicinal Chemistry Aminopyridine 8ETumor BiologyKinase DomainNovel TherapyMedicine	2014	115

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