Danielle Orfila

Discovery of phenoxyindazoles and phenylthioindazoles as RORγ inverse agonists

Gilles Ouvry, Claire Bouix‐Peter, Fabrice Ciesielski et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 37 citations · Full text

Molecular Pharmacology, Drug Target, Medicine +6

A topical treatment containing heat‐treated <i>Lactobacillus johnsonii</i> NCC 533 reduces <i>Staphylococcus aureus</i> adhesion and induces antimicrobial peptide expression in an in vitro reconstructed human epidermis model

Carine Rosignoli, Séverine Thibaut de Ménonville, Danielle Orfila et al. · Experimental Dermatology · 2018 · 37 citations

Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory Acne

Jean‐François Fournier, Laurence Clary, Sandrine Chambon et al. · Journal of Medicinal Chemistry · 2018 · 18 citations · Full text

Pharmaceutical Science, Immunology, Peptide Science +18

Sulfoximines as potent RORγ inverse agonists

Gilles Ouvry, Franck Bihl, Claire Bouix‐Peter et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 17 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +6

Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis

Gilles Ouvry, Nicolas Atrux‐Tallau, Franck Bihl et al. · ChemMedChem · 2018 · 15 citations