João Pedro Lopes

The physiological effects of caffeine on synaptic transmission and plasticity in the mouse hippocampus selectively depend on adenosine A1 and A2A receptors

João Pedro Lopes, Anna Pliássova, Rodrigo A. Cunha · Biochemical Pharmacology · 2019 · 113 citations

Life Sciences, Neuroscience, Pharmacology +17

Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine

Francisco Q. Gonçalves, João Pedro Lopes, Henrique B. Silva et al. · Neurobiology of Disease · 2019 · 104 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

António C. Silva, Cristina Lemos, Francisco Q. Gonçalves et al. · Neurobiology of Disease · 2018 · 87 citations · Full text

Life Sciences, Neuroscience, Pharmacology +12

Neurodegeneration in an Aβ‐induced model of Alzheimer’s disease: the role of Cdk5

João Pedro Lopes, Catarina R. Oliveira, Paula Agostinho · Aging Cell · 2009 · 85 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Pharmacological Characterization of Memoquin, a Multi-Target Compound for the Treatment of Alzheimer's Disease

Valeria Capurro, Perrine Busquet, João Pedro Lopes et al. · PLoS ONE · 2013 · 79 citations · Full text

Medicine, Neuroscience, Pharmacology +17