Thomas Hirschberger

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease

Jens A. Wagner, Sergey Ryazanov, Andrei Leonov et al. · Acta Neuropathologica · 2013 · 439 citations · Full text

Identification of Anti-prion Compounds as Efficient Inhibitors of Polyglutamine Protein Aggregation in a Zebrafish Model

Niclas W. Schiffer, Sarah A. Broadley, Thomas Hirschberger et al. · Journal of Biological Chemistry · 2006 · 100 citations · Full text

Neurodegenerative Diseases, Developmental Biology, Biochemistry +15

Systematic Identification of Antiprion Drugs by High-Throughput Screening Based on Scanning for Intensely Fluorescent Targets

Uwe Bertsch, Konstanze F. Winklhofer, Thomas Hirschberger et al. · Journal of Virology · 2005 · 63 citations · Full text

Extracting Markov Models of Peptide Conformational Dynamics from Simulation Data

Verena Schultheis, Thomas Hirschberger, Heiko Carstens et al. · Journal of Chemical Theory and Computation · 2005 · 44 citations

Engineering, Transfer Operator, Molecular Biology +19

Structural Instability of the Prion Protein upon M205S/R Mutations Revealed by Molecular Dynamics Simulations

Thomas Hirschberger, Martina Stork, Bernhard Schropp et al. · Biophysical Journal · 2006 · 39 citations · Full text

Biomolecular Structure Prediction, Protein Folding, Medicine +13