Mahmoud S. Alghamri

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response

Felipe J. Núñez, Flor Mendez, Padma Kadiyala et al. · Science Translational Medicine · 2019 · 290 citations · Full text

Medicine, Molecular Biology, Oncology +17

Systemic Delivery of an Adjuvant CXCR4–CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy

Mahmoud S. Alghamri, Kaushik Banerjee, Anzar Mujeeb et al. · ACS Nano · 2022 · 144 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice

Padma Kadiyala, Stephen V. Carney, Jessica C. Gauss et al. · Journal of Clinical Investigation · 2020 · 139 citations · Full text

Medicine, Cancer Biology, Oncology +16

G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy

Mahmoud S. Alghamri, Brandon L. McClellan, Ruthvik Avvari et al. · Science Advances · 2021 · 90 citations · Full text

Medicine, Cancer Biology, Oncology +17

H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models

Santiago Haase, Kaushik Banerjee, Anzar Mujeeb et al. · Journal of Clinical Investigation · 2022 · 86 citations · Full text

Life Sciences, Genetics, Oncology +17