Benedikt S. Saller

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

Katharina S. Schneider, Christina J. Groß, Roland F. Dreier et al. · Cell Reports · 2017 · 296 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

Shaima’a Hamarsheh, Benedikt S. Saller, Susanne Unger et al. · Nature Communications · 2020 · 146 citations · Full text

Medicine, Hematology, Oncology +17

Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation

Benedikt S. Saller, Svenja Wöhrle, Larissa Fischer et al. · Immunity · 2024 · 66 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile

Julian Merz, A. Nettesheim, Sunaina von Garlen et al. · Purinergic Signalling · 2021 · 36 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis

Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković et al. · Science Signaling · 2023 · 25 citations

Life Sciences, Immunology, Medicinal Chemistry +17