Graham L. Simpson

Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

Jingsong Yang, Nino Campobasso, Mangatt P. Biju et al. · Chemistry & Biology · 2011 · 113 citations

Signal Transduction, Cell Signaling, Myristoyl Binding Site +11

Design and Application of a DNA-Encoded Macrocyclic Peptide Library

Zhengrong Zhu, Alex Shaginian, LaShadric C. Grady et al. · ACS Chemical Biology · 2017 · 103 citations

Ladder Polyether Synthesis via Epoxide-Opening Cascades Using a Disappearing Directing Group

Graham L. Simpson, Timothy P. Heffron, Estı́baliz Merino et al. · Journal of the American Chemical Society · 2006 · 78 citations

Ladder Polyether Synthesis, Engineering, Trimethylsilyl Group +17

Improving the passive permeability of macrocyclic peptides: Balancing permeability with other physicochemical properties

Praew Thansandote, Robert M. Harris, Hannah L. Dexter et al. · Bioorganic & Medicinal Chemistry · 2014 · 64 citations

Peptide Engineering, Peptide Library, Peptide Synthesis +5

Synthesis and Pharmacological Characterization of Novel Analogues of the Nicotinic Acetylcholine Receptor Agonist (±)-UB-165

Christopher G. V. Sharples, Gunter Karig, Graham L. Simpson et al. · Journal of Medicinal Chemistry · 2002 · 52 citations · Full text

Pharmacological Characterization, Novel Analogues, Chemical Biology +17