Manmohan R. Leleti

Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study

Pirow Bekker, Daniel J. Dairaghi, Lisa Seitz et al. · PLoS ONE · 2016 · 144 citations · Full text

Immunology, Potent C5ar Antagonist, Receptor Inhibitor +21

Discovery of AB680: A Potent and Selective Inhibitor of CD73

Kenneth V. Lawson, Jarosław Kalisiak, Erick A. Lindsey et al. · Journal of Medicinal Chemistry · 2020 · 83 citations · Full text

Safety, tolerability, and pharmacology of AB928, a novel dual adenosine receptor antagonist, in a randomized, phase 1 study in healthy volunteers

Lisa Seitz, Lixia Jin, Manmohan R. Leleti et al. · Investigational New Drugs · 2018 · 60 citations

Molecular Pharmacology, Functional Selectivity, Healthy Volunteers +6

Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73

Joel W. Beatty, Erick A. Lindsey, Rhiannon Thomas‐Tran et al. · Journal of Medicinal Chemistry · 2020 · 55 citations · Full text

Discovery of Potent and Selective PI3Kγ Inhibitors

Samuel L. Drew, Rhiannon Thomas‐Tran, Joel W. Beatty et al. · Journal of Medicinal Chemistry · 2020 · 36 citations · Full text