Leonardo Pisani

Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors:  Safinamide and Coumarin Analogs

Claudia Binda, Jin Wang, Leonardo Pisani et al. · Journal of Medicinal Chemistry · 2007 · 591 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Discovery of a Novel Class of Potent Coumarin Monoamine Oxidase B Inhibitors: Development and Biopharmacological Profiling of 7-[(3-Chlorobenzyl)oxy]-4-[(methylamino)methyl]-2<i>H</i>-chromen-2-one Methanesulfonate (NW-1772) as a Highly Potent, Selective, Reversible, and Orally Active Monoamine Oxidase B Inhibitor

Leonardo Pisani, Giovanni Muncipinto, Teresa Fabiola Miscioscia et al. · Journal of Medicinal Chemistry · 2009 · 106 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Design and Optimization of Multitarget-Directed 2<i>H</i>-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

Roberta Farina, Leonardo Pisani, Marco Catto et al. · Journal of Medicinal Chemistry · 2015 · 99 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Aromatase Inhibitors Selective over 17-α-Hydroxylase/C17−20 Lyase

Angela Stefanachi, Angelo D. Favia, Orazio Nicolotti et al. · Journal of Medicinal Chemistry · 2011 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents

Leonardo Pisani, Roberta Farina, Marco Catto et al. · Journal of Medicinal Chemistry · 2016 · 90 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17