Roberta Farina

Structure-Based Design and Optimization of Multitarget-Directed 2<i>H</i>-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

Roberta Farina, Leonardo Pisani, Marco Catto et al. · Journal of Medicinal Chemistry · 2015 · 98 citations · Full text

Pharmacotherapy, Chemical Biology, Pharmaceutical Chemistry +16

Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents

Leonardo Pisani, Roberta Farina, Marco Catto et al. · Journal of Medicinal Chemistry · 2016 · 88 citations · Full text

Drug Target, Hmao B, Neurochemical Biomarkers +21

In silico design of novel 2H-chromen-2-one derivatives as potent and selective MAO-B inhibitors

Leonardo Pisani, Roberta Farina, Orazio Nicolotti et al. · European Journal of Medicinal Chemistry · 2014 · 60 citations · Full text

Novel 2H-chromen-2-one Derivatives, Combinatorial Chemistry, Medicinal Chemistry +10

Searching for Multi-Targeting Neurotherapeutics against Alzheimer’s: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif

Leonardo Pisani, Roberta Farina, Ramón Soto‐Otero et al. · Molecules · 2016 · 50 citations · Full text

2H-chromen-2-one Structural Motif, Drug Target, Compound 3H +21

Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors

Leonardo Pisani, Rosa Maria Iacobazzi, Marco Catto et al. · European Journal of Medicinal Chemistry · 2018 · 47 citations · Full text

Alkyl Nitrates, Medicinal Chemistry, Inhibitory Activity +11