Laura Trescott

Structural Insights into Estrogen Receptor α Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation

Yuanyuan Jiang, Laura Trescott, Joshua Holcomb et al. · Journal of Molecular Biology · 2014 · 55 citations

Histone Modifications, Environmental Signaling, Epigenetic Change +18

Crystallographic analysis of NHERF1–PLCβ3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer

Yuanyuan Jiang, Shuo Wang, Joshua Holcomb et al. · Biochemical and Biophysical Research Communications · 2014 · 18 citations

Signal Transduction, Signaling Pathway, Pancreatic Cancer +10

New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping

Yuanyuan Jiang, Guorong Lu, Laura Trescott et al. · PLoS ONE · 2013 · 16 citations · Full text

Conformational Dynamics, Crystal Structure, Engineering +17

Structural insights into PDZ-mediated interaction of NHERF2 and LPA2, a cellular event implicated in CFTR channel regulation

Joshua Holcomb, Yuanyuan Jiang, Guorong Lu et al. · Biochemical and Biophysical Research Communications · 2014 · 15 citations · Full text

Cftr Channel Regulation, Signal Transduction, Molecular Physiology +14

Crystal structure of the NHERF1 PDZ2 domain in complex with the chemokine receptor CXCR2 reveals probable modes of PDZ2 dimerization

Joshua Holcomb, Yuanyuan Jiang, Xiaoqing Guan et al. · Biochemical and Biophysical Research Communications · 2014 · 11 citations

Crystal Structure, Nherf1 Pdz2 Domain, Biochemistry +10