Sebastiaan De Schepper

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens et al. · Nature Neuroscience · 2019 · 1K citations · Full text

Cell Lineage, Developmental Biology, Single Cell Sequencing +7

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

Sebastiaan De Schepper, Simon Verheijden, Javier Aguilera‐Lizarraga et al. · Cell · 2018 · 550 citations · Full text

Inflammation, Intestinal Homeostasis, Immunology +5

Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung

Joey Schyns, Qiang Baï, Cecilia Ruscitti et al. · Nature Communications · 2019 · 318 citations · Full text

Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease

Sebastiaan De Schepper, Judy Z. Ge · Nature Neuroscience · 2023 · 254 citations · Full text

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

Wiebe Vanhove, Paul Peeters, Dominiek Staelens et al. · Inflammatory Bowel Diseases · 2015 · 133 citations · Full text