lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Yuanyuan Lu, Xiaodi Zhao, Qi Liu, +19

Nature Medicine

Transcriptional RegulationGeneticsRna BiologyLncrna Mir100hg-derived Mir-100Long Non-coding Rna +8

Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression

Hao Liu, Danxiu Li, Lina Sun, +24

Molecular Cancer

PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells

Ming-Zhi Zhang, Weiyi Mai, Cunxi Li, +23

Proceedings of the National Academy of Sciences

Fibrocystin/Polyductin Modulates Renal Tubular Formation by Regulating Polycystin-2 Expression and Function

Ingyu Kim, Yulong Fu, Kwokyin Hui, +11

Journal of the American Society of Nephrology

Renal PathologyRenal InflammationPathologyDisease Gene IdentificationRenal Function +17

Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer

Cunxi Li, Haiting Ma, Yang Wang, +11

Journal of Clinical Investigation

PathologyCancer BiologyTumor BiologyCell Surface Cdh1Signaling Pathway +17

miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44

Lina Sun, Ying Fang, Xin Wang, +17

Theranostics

Conditional Mutation of Pkd2 Causes Cystogenesis and Upregulates β-Catenin

Ingyu Kim, Tianbing Ding, Yulong Fu, +12

Journal of the American Society of Nephrology

Conditional MutationDevelopmental BiologyTotal Body EdemaSignaling PathwayMedicine +8

Myristoylated Naked2 escorts transforming growth factor α to the basolateral plasma membrane of polarized epithelial cells

Cunxi Li, Jeffrey L. Franklin, Ramona Graves‐Deal, +3

Proceedings of the National Academy of Sciences

Polycystin-2 Expression Is Regulated by a PC2-binding Domain in the Intracellular Portion of Fibrocystin

Ingyu Kim, Cunxi Li, Dan Liang, +5

Journal of Biological Chemistry

Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth

Dandan Li, Youyu Zhang, Kun Liu, +10

Laboratory Investigation

InflammationInflammatory ResponsesAnti-inflammatoryColitis-associated TumorigenesisMedicine +6