Nikolai Galitsky

Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of<i>Bacillus thuringiensis</i>

Nikolai Galitsky, Vivian Cody, Andrzej Wojtczak et al. · Acta Crystallographica Section D Biological Crystallography · 2001 · 185 citations

Life Sciences, Biochemistry, Entomology +16

Methotrexate-resistant Variants of Human Dihydrofolate Reductase with Substitutions of Leucine 22

William S. Lewis, Vivian Cody, Nikolai Galitsky et al. · Journal of Biological Chemistry · 1995 · 145 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Design, Synthesis, and X-ray Crystal Structure of a Potent Dual Inhibitor of Thymidylate Synthase and Dihydrofolate Reductase as an Antitumor Agent

Aleem Gangjee, Jianming Yu, John J. McGuire et al. · Journal of Medicinal Chemistry · 2000 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Ligand-Induced Conformational Changes in the Crystal Structures of<i>Pneumocystis carinii</i>Dihydrofolate Reductase Complexes with Folate and NADP⁺^,

Vivian Cody, Nikolai Galitsky, Dawn M. Rak et al. · Biochemistry · 1999 · 62 citations

Natural Sciences, Biochemistry, Molecular Biology +17

Structure-Based Design and Synthesis of Lipophilic 2,4-Diamino-6-Substituted Quinazolines and Their Evaluation as Inhibitors of Dihydrofolate Reductases and Potential Antitumor Agents

Aleem Gangjee, Anup Vidwans, Anil Vasudevan et al. · Journal of Medicinal Chemistry · 1998 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13