Toshio Goto

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.

Toru Kino, Hiroshi Hatanaka, MICHISANE HASHIMOTO et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Biochemistry, Pharmacology +10

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.

Toru Kino, Hiroshi Hatanaka, Susumu Miyata et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Immunology, Pharmacology +9

Structure of FK506, a novel immunosuppressant isolated from Streptomyces

Hirokazu Tanaka, Akio Kuroda, Hiroshi Marusawa et al. · Journal of the American Chemical Society · 1987 · 514 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

FR901228, a novel antitumor bicyclic depsipeptide produced by chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity.

Hirotsugu Ueda, Hidenori Nakajima, Yasuhiro Hori et al. · The Journal of Antibiotics · 1994 · 488 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Structure and Molecular Stacking of Anthocyanins—Flower Color Variation

Toshio Goto, Tadao Kondo · Angewandte Chemie International Edition in English · 1991 · 477 citations

Life Sciences, Biochemistry, Chemistry +17