Shigetoshi Kikuchi - Concepedia

Author

Shigetoshi Kikuchi

Astellas Pharma (Japan)

Also Known As

Kikuchi, Shuta, S. KIKUCHI, Shigetoshi Kikuchi, Shuta Kikuchi

Publications

296

Citations

H-Index

Concepts

All Affiliations

Astellas Pharma (Japan)Tohoku University Okayama University

About

Shigetoshi Kikuchi is an author at Astellas Pharma (Japan) specializing in drug development, medicinal chemistry, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	115
2	Natural Sciences	5	5	167
3	Biochemistry	4	4	131
4	Biomolecular Engineering	3	3	114
5	Engineering	1	1	65

Shigetoshi Kikuchi

Publications

290

Citations

H-Index

Page 1

	Year	Citations
Optical Resolution of 2-Amino-1,2-diphenylethanol by Preferential Crystallization and Its Utilization in Fractional Crystallization and Enantioselective Reduction of Prochiral Ketones Kazuhiko Saigo, Shigeo Ogawa, Shigetoshi Kikuchi, Bulletin of the Chemical Society of Japan Optical MaterialsEngineeringFractional CrystallizationOrganic ChemistryChemistry	1982	65
Total Synthesis of Brevenal Hiroyoshi Takamura, Shigetoshi Kikuchi, Yuichi Nakamura, Organic Letters	2009	65
Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2 Ikumi Kuriwaki, Minoru Kameda, Hiroyuki Hisamichi, Bioorganic & Medicinal Chemistry Medicinal ChemistryPharmaceutical ScienceMedicineDrug DiscoveryNatural Sciences	2020	36
Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition Wataru Hamaguchi, Naoyuki Masuda, Mai Isomura, Bioorganic & Medicinal Chemistry Combinatorial ChemistryMedicinal ChemistryNovel Benzimidazole DerivativesBiochemistryPhosphodiesterase 10A	2013	33
Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition Wataru Hamaguchi, Naoyuki Masuda, Satoshi Miyamoto, Bioorganic & Medicinal Chemistry Medicinal ChemistryBiochemistryPhosphodiesterase 10AMedicineNatural Sciences	2014	22
Total synthesis of brevenal Hiroyoshi Takamura, Yuji Yamagami, Takayuki Kishi, Tetrahedron Total SynthesisOrganic ChemistrySynthesis MethodChemistryNatural Product Synthesis	2010	21
Solvent-Controlled Stereoselective Formation of a Cyclic Ether in the Lewis Acid-Mediated Allylation of an α-Chloroacetoxy Acyclic Ether. Very High Stereoselectivity in CH<sub>3</sub>CN vs Low Stereoselectivity in CH<sub>2</sub>Cl<sub>2</sub> Ilya D. Gridnev, Shigetoshi Kikuchi, Abeda S. Touchy, The Journal of Organic Chemistry	2007	14
Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency Ikumi Kuriwaki, Minoru Kameda, Kazuhiko Iikubo, Bioorganic & Medicinal Chemistry Medicinal ChemistryPharmaceutical ScienceMedicineSystemic ExposurePharmacological Agent	2021	13
Discovery of ASP5878: Synthesis and structure–activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel inhibitory activity Ikumi Kuriwaki, Minoru Kameda, Kazuhiko Iikubo, Bioorganic & Medicinal Chemistry Medicinal ChemistryPharmaceutical ScienceBiochemistryNatural SciencesMedicine	2022	11
Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436 Wataru Hamaguchi, Naoyuki Masuda, Satoshi Miyamoto, Bioorganic & Medicinal Chemistry	2015	10

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