Mark A. Lehrman

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

Mark A. Lehrman, Wolfgang J. Schneider, Thomas C. Südhof et al. · Science · 1985 · 463 citations

Signal Transduction, Biochemistry, Natural Sciences +14

The Molecular Chaperone Calnexin Binds Glc1Man9GlcNAc2 Oligosaccharide as an Initial Step in Recognizing Unfolded Glycoproteins

Felecia E. Ware, Aikaterini Vassilakos, Per A. Peterson et al. · Journal of Biological Chemistry · 1995 · 419 citations · Full text

Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway

Zhao V. Wang, Yingfeng Deng, Ningguo Gao et al. · Cell · 2014 · 397 citations · Full text

Protein Function, Biochemistry, Protein Assembly +8

The J. D. mutation in familial hypercholesterolemia: Amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors

Claire Davis, Mark A. Lehrman, David W. Russell et al. · Cell · 1986 · 375 citations

J. D. Mutation, Familial Hypercholesterolemia, Lipid Disorder +10

Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain

Mark A. Lehrman, Joseph L. Goldstein, Michael S. Brown et al. · Cell · 1985 · 300 citations

Knockout Mouse, Signal Transduction, Internalization-defective Ldl Receptors +9