Concepedia

Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway

Zhao V. Wang, Yingfeng Deng, Ningguo Gao, Zully Pedrozo, Dan L. Li, Cyndi R. Morales, Alfredo Criollo, Xiang Luo, Wei Tan, Nan Jiang,

Cell · 2014 · 407 citations · 34 references

Open access

Concepts

Life SciencesBiochemistryMolecular BiologyGene ExpressionProtein FoldingSignal TransductionCo-translational Protein FoldingEnzyme FunctionProtein Folding PathwaysProtein MisfoldingProtein RefoldingProtein SynthesisFolding PathwaysHexosamine Biosynthesis PathwayHexosamine Biosynthetic PathwayProtein Complex FoldingProtein Misfolding Signaling ResponsesUnfolded Protein ResponseUnfolded Protein Response Genes

References

34

THE MAMMALIAN UNFOLDED PROTEIN RESPONSE

Martin Schröder, Randal J. Kaufman · Annual Review of Biochemistry · 2005 · 3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

Arthur Kaser, Ann–Hwee Lee, André Franke et al. · Cell · 2008 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

Neal N. Iwakoshi, Ann–Hwee Lee, Prasanth Vallabhajosyula et al. · Nature Immunology · 2003 · 866 citations

Life Sciences, Cell Biology, Molecular Biology +13

XBP1 Is Essential for Survival under Hypoxic Conditions and Is Required for Tumor Growth

Lorenzo Romero‐Ramírez, Hongbin Cao, Daniel W. Nelson et al. · Cancer Research · 2004 · 570 citations

Life Sciences, Molecular Biology, Oncology +17

Dynamic O-GlcNAc Modification of Nucleocytoplasmic Proteins in Response to Stress

Natasha E. Zachara, Niall O'Donnell, Win D. Cheung et al. · Journal of Biological Chemistry · 2004 · 570 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17