Weldon P. Phillips

Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6- benzylguanine plus BCNU

S L Gerson, Weldon P. Phillips, Michael B. Kastan et al. · Blood · 1996 · 85 citations · Full text

Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to <i>O</i> ⁶ -benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea

Jane Reese, Omer N. Koç, Keun Myoung Lee et al. · Proceedings of the National Academy of Sciences · 1996 · 82 citations

Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects.

Pierre-M Girard, Nicolas Foray, Markus Stümm et al. · PubMed · 2000 · 70 citations

Chromatin, Genome Instability, Dna Damage +14

O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.

Weldon P. Phillips, James K. V. Willson, Sanford D. Markowitz et al. · PubMed · 1997 · 23 citations

Chemoprevention Strategy, Cancer Biology, Tumor Biology +17

Acquired resistance to O   6 -benzylguanine plus chloroethylnitrosoureas in human breast cancer

Weldon P. Phillips, Stanton L. Gerson · Cancer Chemotherapy and Pharmacology · 1999 · 11 citations

Tumor Biology, Breast Oncology, Biochemistry +10