Christien Bednarski

Versatile and Efficient Genome Editing in Human Cells by Combining Zinc-Finger Nucleases With Adeno-Associated Viral Vectors

Eva-Maria Händel, Katharina Gellhaus, Kafaitullah Khan et al. · Human Gene Therapy · 2011 · 62 citations · Full text

Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases

Moritz J. Schmidt, Ashish Gupta, Christien Bednarski et al. · Nature Communications · 2021 · 55 citations · Full text

Engineering, Molecular Biology, Gene Delivery +19

Targeted Integration of a Super-Exon into the CFTR Locus Leads to Functional Correction of a Cystic Fibrosis Cell Line Model

Christien Bednarski, Katja Tomczak, Beate vom Hövel et al. · PLoS ONE · 2016 · 52 citations · Full text

Inflammatory Lung Disease, Biomedical Research, Molecular Biology +25

Generation of a gene-corrected isogenic control iPSC line from cystic fibrosis patient-specific iPSCs homozygous for p.Phe508del mutation mediated by TALENs and ssODN

Sylvia Merkert, Christien Bednarski, Gudrun Göhring et al. · Stem Cell Research · 2017 · 40 citations · Full text

Engineering, Genetics, Molecular Biology +21

The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42

Marta Rosário, Renate Franke, Christien Bednarski et al. · The Journal of Cell Biology · 2007 · 36 citations · Full text

Developmental Biology, Signal Transduction, Synaptic Signaling +15