D E Zhang

AML1–ETO downregulates the granulocytic differentiation factor C/EBPα in t(8;21) myeloid leukemia

Thomas Pabst, Beatrice U. Mueller, Nari Harakawa et al. · Nature Medicine · 2001 · 462 citations

Hematological Malignancy, Hematology, Immunology +8

The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor.

D E Zhang, Christopher J. Hetherington, H M Chen et al. · Molecular and Cellular Biology · 1994 · 400 citations · Full text

Immune Regulation, Immunology, Immunologic Mechanism +19

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene

Donald Yergeau, Christopher J. Hetherington, Qing Wang et al. · Nature Genetics · 1997 · 356 citations

Knockout Mouse, Cell Lineage, Developmental Biology +10

PU.1 (Spi-1) autoregulates its expression in myeloid cells.

Huimin Chen, Dominique Ray-Gallet, Peng Zhang et al. · PubMed · 1995 · 215 citations

Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1).

D E Zhang, Kenta Fujioka, Christopher J. Hetherington et al. · Molecular and Cellular Biology · 1994 · 200 citations · Full text

Region Ii, Tissue Specificity, Immunology +16