Leigh M. Jacobs

Absorption, distribution, metabolism and excretion of intravenously and orally administered tetrabromobisphenol A [2,3-dibromopropyl ether] in male Fischer-344 rats

Gabriel A. Knudsen, Leigh M. Jacobs, Robert K. Kuester et al. · Toxicology · 2007 · 44 citations

Pharmacological Study, Medicine, Male Fischer-344 Rats +6

P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain

Margaret E. Tome, Joseph M. Herndon, Charles Schaefer et al. · Journal of Cerebral Blood Flow & Metabolism · 2016 · 22 citations · Full text

Pain Medicine, Neuropathic Pain, Molecular Pain +21

Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels

Charles Schaefer, Nathan B. Arkwright, Leigh M. Jacobs et al. · PLoS ONE · 2018 · 22 citations · Full text

Morphine Tolerance, Pain Medicine, Neurotransmitter +27

Acute pain alters P-glycoprotein-containing protein complexes in rat cerebral microvessels: Implications for P-glycoprotein trafficking

Margaret E. Tome, Chelsea Jarvis, Charles Schaefer et al. · Journal of Cerebral Blood Flow & Metabolism · 2018 · 20 citations · Full text

Pain Medicine, Immunology, Molecular Pain +26

Identification of P‐glycoprotein co‐fractionating proteins and specific binding partners in rat brain microvessels

Margaret E. Tome, Charles Schaefer, Leigh M. Jacobs et al. · Journal of Neurochemistry · 2015 · 17 citations · Full text

Molecular Biology, Neurochemical Biomarkers, Pgp Activity +20