Christopher J. Lunniss

Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease

Kenneth Down, Augustin Amour, Ian T. Baldwin et al. · Journal of Medicinal Chemistry · 2015 · 130 citations

Asthma, Acute Lung Injury, Pi3kδ Potency +24

Addressing species specific metabolism and solubility issues in a quinoline series of oral PDE4 inhibitors

Christopher J. Lunniss, Colin Eldred, Natalie E. Aston et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 35 citations · Full text

Species Specific Metabolism, Medicinal Chemistry, Biochemistry +9

Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors

Lorraine C. Axford, Piyush K. Agarwal, Kelly H. Anderson et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 35 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Biochemistry +8

Biological Evaluation of Benzothiazole Ethyl Urea Inhibitors of Bacterial Type II Topoisomerases

Neil R. Stokes, Helena Thomaides‐Brears, Stephanie Barker et al. · Antimicrobial Agents and Chemotherapy · 2013 · 34 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Antimicrobial Chemotherapy +22

Complementary Reactions of Allylic Carbamates Using Palladium(II): Formation of Oxazolidinones or Allylic Amides from a Common Precursor

S. Christie, Adam D. Warrington, Christopher J. Lunniss · Synthesis · 2008 · 33 citations

Cross-coupling Reaction, Common Precursor, Engineering +12