Philip Stavrides

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

Ju‐Hyun Lee, Dun‐Sheng Yang, Chris N. Goulbourne et al. · Nature Neuroscience · 2022 · 570 citations · Full text

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

Dun-Sheng Yang, Philip Stavrides, Panaiyur S. Mohan et al. · Brain · 2010 · 422 citations · Full text

Mitophagy, Tgcrnd8 Mice, Cell Death +21

Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer's Disease

Dun‐Sheng Yang, Asok Kumar, Philip Stavrides et al. · American Journal Of Pathology · 2008 · 160 citations · Full text

Autophagy Cross Talk, Cell Autophagy, Mitophagy +14

Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer’s Disease

Anna Pensalfini, Seonil Kim, Shivakumar Subbanna et al. · Cell Reports · 2020 · 113 citations · Full text

Endosomal Dysfunction Induced, Rab5 Overactivation, Cell Death +25

Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits

Dun-Sheng Yang, Philip Stavrides, Asok Kumar et al. · Brain · 2014 · 112 citations · Full text

Mitophagy, Neurochemical Biomarkers, Defective Macroautophagic Turnover +24