Kevin Chiu

A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee

V. Deshmukh, Haide Hu, Charlene F. Barroga et al. · Osteoarthritis and Cartilage · 2017 · 223 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Modulation of the Wnt pathway through inhibition of CLK2 and DYRK1A by lorecivivint as a novel, potentially disease-modifying approach for knee osteoarthritis treatment

V. Deshmukh, Alyssa L. O'Green, Carine Bossard et al. · Osteoarthritis and Cartilage · 2019 · 193 citations · Full text

Medicine, Orthopaedic Surgery, Pharmacology +17

Cell-Extrinsic Effects of Tumor ER Stress Imprint Myeloid Dendritic Cells and Impair CD8+ T Cell Priming

Navin R. Mahadevan, Veronika Anufreichik, Jeffrey J. Rodvold et al. · PLoS ONE · 2012 · 154 citations · Full text

Life Sciences, Immunology, Oncology +17

The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models

Betty Y. Tam, Kevin Chiu, Heekyung Chung et al. · Cancer Letters · 2019 · 143 citations · Full text

Medicine, Oncology, Pharmacology +17

Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells

Jeffrey J. Rodvold, Kevin Chiu, Nobuhiko Hiramatsu et al. · Science Signaling · 2017 · 109 citations · Full text

Life Sciences, Cell Biology, Cell Signaling +1