Ana L. Portillo

Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment

Sophie M. Poznanski, Kanwaldeep Singh, Tyrah M. Ritchie et al. · Cell Metabolism · 2021 · 253 citations · Full text

Tumor Biology, Cancer Immunosurveillance, Medicine +10

Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors

Ana L. Portillo, Richard T. Hogg, Sophie M. Poznanski et al. · iScience · 2021 · 67 citations · Full text

Expanded human NK cells from lung cancer patients sensitize patients’ PDL1−negative tumors to PD1-blockade therapy

Sophie M. Poznanski, Tyrah M. Ritchie, Isabella Y. Fan et al. · Journal for ImmunoTherapy of Cancer · 2021 · 36 citations · Full text

Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells

Alyssa Vito, Omar Salem, Nader El-Sayes et al. · Communications Biology · 2021 · 23 citations · Full text

Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity

Elizabeth Balint, Emily Feng, Elizabeth C. Giles et al. · Nature Communications · 2024 · 22 citations · Full text