Yan Huang

Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia.

Jennifer Ziello, Ion S. Jovin, Yan Huang · PubMed · 2007 · 670 citations

Medicine, Cancer Biology, Oncology +15

Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis

Nan Tang, Lianchun Wang, Jeffrey D. Esko et al. · Cancer Cell · 2004 · 533 citations

Medicine, Molecular Biology, Oncology +14

A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function

Frank J. Giordano, Hans‐Peter Gerber, Simon‐Peter Williams et al. · Proceedings of the National Academy of Sciences · 2001 · 370 citations · Full text

Life Sciences, Cardiology, Physiology +17

Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice

Takahisa Murata, Michelle I. Lin, Yan Huang et al. · The Journal of Experimental Medicine · 2007 · 247 citations · Full text

Life Sciences, Cell Biology, Physiology +17

ATR inhibitor AZD6738 enhances the antitumor activity of radiotherapy and immune checkpoint inhibitors by potentiating the tumor immune microenvironment in hepatocellular carcinoma

Hailong Sheng, Yan Huang, Yazhi Xiao et al. · Journal for ImmunoTherapy of Cancer · 2020 · 226 citations · Full text

Medicine, Immunology, Oncology +17