Epigenetic Profiling of Cutaneous T-Cell Lymphoma: Promoter Hypermethylation of Multiple Tumor Suppressor Genes Including <i>BCL7a</i>, <i>PTPRG</i>, and <i>p73</i>

Remco van Doorn, Willem H. Zoutman, Remco Dijkman, +9

Journal of Clinical Oncology

MicroRNA-21 Expression in CD4+ T Cells Is Regulated by STAT3 and Is Pathologically Involved in Sézary Syndrome

Leslie van der Fits, Marloes S. van Kester, Yongjun Qin, +6

Journal of Investigative Dermatology

Sézary SyndromeAutoimmune DiseaseMicrorna-21 ExpressionT-regulatory CellImmunology +8

Fine-Mapping Chromosomal Loss at 9p21: Correlation with Prognosis in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type

Nancy J. Senff, Willem H. Zoutman, Maarten H. Vermeer, +15

Journal of Investigative Dermatology

Hematological MalignancyLymphoid NeoplasiaOncologyMedicineHistopathology +9

Evaluation of Immunophenotypic and Molecular Biomarkers for Sézary Syndrome Using Standard Operating Procedures: A Multicenter Study of 59 Patients

Stéphanie E. Boonk, Willem H. Zoutman, Anne Marie‐Cardine, +23

Journal of Investigative Dermatology

Molecular BiomarkersAutoimmune DiseaseImmunodeficienciesSurgical PathologyHematology +6

A Lack of Birbeck Granules in Langerhans Cells Is Associated with a Naturally Occurring Point Mutation in the Human Langerin Gene

Pauline Verdijk, Remco Dijkman, Elsemieke I. Plasmeijer, +4

Journal of Investigative Dermatology

Cell DivisionPoint MutationPathologyBirbeck GranulesHuman Langerin Gene +2

Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndrome

Katarzyna Iżykowska, Grzegorz K. Przybylski, Claudia Gand, +9

Oncotarget

Improved Sézary cell detection and novel insights into immunophenotypic and molecular heterogeneity in Sézary syndrome

Safa Najidh, Cornelis P. Tensen, Alita J. van der Sluijs‐Gelling, +11

Blood

Digital PCR-Based T-cell Quantification–Assisted Deconvolution of the Microenvironment Reveals that Activated Macrophages Drive Tumor Inflammation in Uveal Melanoma

Mark J. de Lange, Rogier J. Nell, Rajshri N. Lalai, +8

Molecular Cancer Research

Exploring the IL-21–STAT3 Axis as Therapeutic Target for Sézary Syndrome

Leslie van der Fits, Jacoba J. Out‐Luiting, Cornelis P. Tensen, +2

Journal of Investigative Dermatology

Clinical ImmunologyImmunodeficienciesImmunologyImmune RegulationPathology +14

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

Oscar P. J. van Linden, Carine Farenc, Willem H. Zoutman, +6

European Journal of Medicinal Chemistry

Small Molecule InhibitorsMedicinal ChemistryDrug TargetBiochemistryNatural Sciences +10