A Lack of Birbeck Granules in Langerhans Cells Is Associated with a Naturally Occurring Point Mutation in the Human Langerin Gene

Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction

Robert M. Horton, Zeling Cai, Steffan N. Ho et al. · BioTechniques · 2013 · 1.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +12

Langerin, a Novel C-Type Lectin Specific to Langerhans Cells, Is an Endocytic Receptor that Induces the Formation of Birbeck Granules

Jenny Valladeau, Odile Ravel, Colette Dezutter‐Dambuyant et al. · Immunity · 2000 · 941 citations

Life Sciences, Cell Biology, Immunology +12

An Electron Microscope Study of Basal Melanocytes and High-Level Clear Cells (Langerhans Cells) in Vitiligo**From the Chester Beatty Research Institute, Royal Cancer Hospital, London, S.W. 3, and the Departments of Anatomy, and Dermatology, St. Mary's Hospital Medical School (University of London) London, W. 2, England.

M. S. C. Birbeck, Aodán S. Breathnach, J. D. Everall · Journal of Investigative Dermatology · 1961 · 809 citations · Full text

Medicine, Dermatology, Pathology +11

The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface

Jenny Valladeau, Valérie Duvert-Frances, Jean‐Jacques Pin et al. · European Journal of Immunology · 1999 · 281 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Birbeck Granules Are Subdomains of Endosomal Recycling Compartment in Human Epidermal Langerhans Cells, Which Form Where Langerin Accumulates

Ray Mc Dermott, Umit Ziylan, Danièle Spehner et al. · Molecular Biology of the Cell · 2002 · 179 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14