Insulin Gene Mutations Resulting in Early-Onset Diabetes: Marked Differences in Clinical Presentation, Metabolic Status, and Pathogenic Effect Through Endoplasmic Reticulum Retention

Gargi Meur, Albane Simon, Nasret Harun, +14

Diabetes

Mitochondrial and ER-Targeted eCALWY Probes Reveal High Levels of Free Zn²⁺

Pauline Chabosseau, Erkan Tuncay, Gargi Meur, +10

ACS Chemical Biology

Zn2+ MobilizationMolecular BiologyMitochondrial BiologyRedox BiologyCellular Physiology +18

Glucose Regulates Free Cytosolic Zn2+ Concentration, Slc39 (ZiP), and Metallothionein Gene Expression in Primary Pancreatic Islet β-Cells

Elisa A. Bellomo, Gargi Meur, Guy A. Rutter

Journal of Biological Chemistry

Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance

Ryan K. Mitchell, Ming Hu, Pauline Chabosseau, +8

Molecular Endocrinology

GeneticsGlucose HomeostasisGene CharacterizationMolecular GeneticsGlucose Tolerance +22

The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion

Antonia Solomou, Gargi Meur, Elisa A. Bellomo, +7

Journal of Biological Chemistry

ImmunologyPancreas TransplantationCellular PhysiologyInsulin SignalingSecretory Granules +17

Glucose-Induced Nuclear Shuttling of ChREBP Is Mediated by Sorcin and Ca2+ Ions in Pancreatic β-Cells

Nafeesa A. Noordeen, Gargi Meur, Guy A. Rutter, +1

Diabetes

Heterologous expression of Arabidopsis NPR1 (AtNPR1) enhances oxidative stress tolerance in transgenic tobacco plants

T. Srinivasan, Koppolu Raja Rajesh Kumar, Gargi Meur, +1

Biotechnology Letters

Plant Molecular BiologyPlant Gene ExpressionEngineeringPlant StressGenetics +9

Constitutive expression of <i>Arabidopsis NPR1 </i>confers enhanced resistance to the early instars of <i>Spodoptera litura </i>in transgenic tobacco

Gargi Meur, Madhusudhan Budatha, Tantravahi Srinivasan, +3

Physiologia Plantarum

BiologyPlant Molecular BiologyPlant ImmunityEngineeringEarly Instars +12

Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells

Philipp A. Gerber, Elisa A. Bellomo, David J. Hodson, +9

Diabetologia

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of <scp>TP</scp> 53 <scp>INP</scp> 1

Marion Seillier, Laurent Pouyet, Prudence N’guessan, +19

EMBO Molecular Medicine