Saijuan Zhang

Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial

Dirk Schürmann, Deanne Jackson Rudd, Saijuan Zhang et al. · The Lancet HIV · 2020 · 95 citations

Medicine, Pharmacokinetics, Pharmacology +17

Safety and pharmacokinetics of islatravir subdermal implant for HIV-1 pre-exposure prophylaxis: a randomized, placebo-controlled phase 1 trial

Randolph P. Matthews, Munjal Patel, Stephanie E. Barrett et al. · Nature Medicine · 2021 · 69 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +15

Safety and Pharmacokinetics of Once-Daily Multiple-Dose Administration of Islatravir in Adults Without HIV

Randolph P. Matthews, Deanne Jackson Rudd, Saijuan Zhang et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 2021 · 31 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

A Phase 1 Study to Evaluate the Drug Interaction Between Islatravir (MK-8591) and Doravirine in Adults Without HIV

Randolph P. Matthews, Deanne Jackson Rudd, Kerry L. Fillgrove et al. · Clinical Drug Investigation · 2021 · 11 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

A phase 1, open‐label study to evaluate the drug interaction between islatravir (MK‐8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females

Wendy Ankrom, Deanne Jackson Rudd, Saijuan Zhang et al. · Journal of the International AIDS Society · 2021 · 11 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17