PamelaSara E. Head

SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination

Waaqo Daddacha, Allyson E. Koyen, Amanda J. Bastien et al. · Cell Reports · 2017 · 207 citations · Full text

ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA

Hui Zhang, PamelaSara E. Head, Waaqo Daddacha et al. · Cell Reports · 2016 · 66 citations · Full text

Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin

PamelaSara E. Head, Sangho Myung, Yong Chen et al. · Science Translational Medicine · 2022 · 48 citations · Full text

Epigenetic Change, Organic Acidemias, Molecular Biology +20

Sirtuin 2 mutations in human cancers impair its function in genome maintenance

PamelaSara E. Head, Hui Zhang, Amanda J. Bastien et al. · Journal of Biological Chemistry · 2017 · 38 citations · Full text

Chromatin, Genome Instability, Radiation Oncology +11

DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining

PamelaSara E. Head, Priya Kapoor-Vazirani, Ganji Purnachandra Nagaraju et al. · Nucleic Acids Research · 2023 · 18 citations · Full text