Jeffrey T. Eummer

Discovery of a 1<i>H</i>-Benzoimidazol-2-yl)-1<i>H</i>-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

Mark D. Wittman, Joan M. Carboni, Ricardo M. Attar et al. · Journal of Medicinal Chemistry · 2005 · 135 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Stereospecific Synthesis and Biological Evaluation of Farnesyl Diphosphate Isomers

Ying Shao, Jeffrey T. Eummer, Richard A. Gibbs · Organic Letters · 1999 · 38 citations

Life Sciences, Biochemistry, Chemistry +12

Discovery of a Fluoroindolo[2,3-<i>a</i>]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11

Mark G. Saulnier, Balu Balasubramanian, Byron H. Long et al. · Journal of Medicinal Chemistry · 2005 · 36 citations · Full text

Medicine, Oncology, Pharmacology +8

Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- <scp>d</scp>-glucopyranosyl]-5<i>H</i>,13<i>H</i>-benzo[<i>b</i>]- thienyl[2,3-<i>a</i>]pyrrolo[3,4-<i>c</i>]carbazole- 5,7(6<i>H</i>)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model

Balu Balasubramanian, Denis R. St. Laurent, Mark G. Saulnier et al. · Journal of Medicinal Chemistry · 2004 · 36 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors

Jeffrey T. Eummer, Barbara S. Gibbs, Todd J. Zahn et al. · Bioorganic & Medicinal Chemistry · 1999 · 31 citations

Pharmacy, Chemistry, Medicinal Chemistry +13