Simon J. Twigden

Synthesis, antitumor activity, and DNA binding properties of a new derivative of amsacrine, N-5-dimethyl-9-[(2-methoxy-4-methylsulfonylamino) phenylamino]-4-acridinecarboxamide.

Bruce C. Baguley, William A. Denny, Graham J. Atwell et al. · PubMed · 1984 · 81 citations

Pharmaceutical Science, Antitumor Activity, Pharmacotherapy +16

Selective toxicity of nitracrine to hypoxic mammalian cells

William R. Wilson, William A. Denny, Simon J. Twigden et al. · British Journal of Cancer · 1984 · 78 citations · Full text

Biochemistry, Reactive Nitrogen Specie, Medicine +7

Triacridine derivative: first DNA tris-intercalating ligand

Graham J. Atwell, Werner Leupin, Simon J. Twigden et al. · Journal of the American Chemical Society · 1983 · 31 citations

Bioorganic Chemistry, Engineering, Altmetric Attention Score +16