Akihiro Hisaka

High plasma linezolid concentration and impaired renal function affect development of linezolid-induced thrombocytopenia

Yoko Nukui, Shuji Hatakeyama, Koh Okamoto et al. · Journal of Antimicrobial Chemotherapy · 2013 · 174 citations

General Framework for the Quantitative Prediction of CYP3A4-Mediated Oral Drug Interactions Based on the AUC Increase by Coadministration of??Standard Drugs

Yoshiyuki Ohno, Akihiro Hisaka, Hiroshi Suzuki · Clinical Pharmacokinetics · 2007 · 166 citations

Medicinal Chemistry, Pharmacological Study, Biochemistry +10

General Framework for the Prediction of Oral Drug Interactions Caused by CYP3A4 Induction from In Vivo Information

Yoshiyuki Ohno, Akihiro Hisaka, Masaki Ueno et al. · Clinical Pharmacokinetics · 2008 · 109 citations

Drug Target, Signal Transduction, Vivo Information +7

Modeling of Rifampicin-Induced CYP3A4 Activation Dynamics for the Prediction of Clinical Drug-Drug Interactions from In Vitro Data

Fumiyoshi Yamashita, Yukako Sasa, Shuya Yoshida et al. · PLoS ONE · 2013 · 97 citations · Full text

Cytochrome P450 3A4, Drug Target, Steady State +13

The Intestinal First-pass Metabolism of Substrates of CYP3A4 and P-glycoprotei—Quantitative Analysis Based on Information from the Literature

Motohiro Kato, Kōji Chiba, Akihiro Hisaka et al. · Drug Metabolism and Pharmacokinetics · 2003 · 91 citations