Atsushi Tomonaga

The Feasibility of an Efficient Drug Design Method with High-Performance Computers

Takefumi Yamashita, Akihiko Ueda, Takashi Mitsui et al. · Chemical and Pharmaceutical Bulletin · 2015 · 26 citations · Full text

Engineering, Free Energy Prediction, Computational Chemistry +24

Identification of allosteric ERK2 inhibitors through in silico biased screening and competitive binding assay

Takayoshi Kinoshita, Hajime Sugiyama, Yurika Mori et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 23 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +12

Knowledge‐Based Identification of the ERK2/STAT3 Signal Pathway as a Therapeutic Target for Type 2 Diabetes and Drug Discovery

Takayoshi Kinoshita, Kentaro Doi, Hajime Sugiyama et al. · Chemical Biology & Drug Design · 2011 · 15 citations

Immunology, Insulin Signaling, Metabolic Syndrome +18

Molecular Dynamics Simulation-Based Evaluation of the Binding Free Energies of Computationally Designed Drug Candidates: Importance of the Dynamical Effects

Takefumi Yamashita, Akihiko Ueda, Takashi Mitsui et al. · Chemical and Pharmaceutical Bulletin · 2014 · 12 citations · Full text

Molecular characterization of genetic mutations in human lactate dehydrogenase (LDH) B (H) variant

Kayoko Sudo, Masato Maekawa, Atsushi Tomonaga et al. · Human Genetics · 1992 · 11 citations

Genetic Analysis, Molecular Characterization, Genetic Mutations +11