Lolke de Haan

Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity

Lolke de Haan, Willem R. Verweij, Marijke Holtrop et al. · Vaccine · 2001 · 118 citations

Vaccination, Mucosal Vaccination, Cross-protection +9

Musosal immunoadjuvant activity of recombinant Escherichia coli heatlabile enterotoxin and its B subunit: Induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with influenza virus surface antigen

Willem R. Verweij, Lolke de Haan, Marijke Holtrop et al. · Vaccine · 1998 · 85 citations

Vaccination, Mucosal Vaccination, Humoral Response +8

Role of G_M1binding in the mucosal immunogenicity and adjuvant activity of the <i>Escherichia coli</i> heat‐labile enterotoxin and its B subunit

Lolke de Haan, WR Verweij, I. K. FEIL et al. · Immunology · 1998 · 83 citations · Full text

The design of chronic toxicology studies of monoclonal antibodies: Implications for the reduction in use of non-human primates

Kathryn Chapman, Laura Andrews, Jeffrey J. Bajramović et al. · Regulatory Toxicology and Pharmacology · 2011 · 67 citations

Autoimmune Disease, Immunotoxicology, Medicine +12

Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin

Lolke de Haan, Walter Verweij, I. Feil et al. · Infection and Immunity · 1996 · 58 citations · Full text

Microbial Toxin, Heat-labile Enterotoxin, Toxinology +13