Tongguan Tian

D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1

Ruonan Zhang, Yajing Yang, Wenjing Dong et al. · Proceedings of the National Academy of Sciences · 2022 · 222 citations · Full text

TET2 Suppresses VHL Deficiency-Driven Clear Cell Renal Cell Carcinoma by Inhibiting HIF Signaling

Xinchao Zhang, Shuyan Li, Jing He et al. · Cancer Research · 2022 · 65 citations

FTY720 attenuates behavioral deficits in a murine model of systemic lupus erythematosus

Dongyan Shi, Tongguan Tian, Yao Shu et al. · Brain Behavior and Immunity · 2018 · 40 citations

Signal Transduction, Autoimmune Disease, Systemic Lupus Erythematosus +8

TET2 is required to suppress mTORC1 signaling through urea cycle with therapeutic potential

Jing He, Mingen Lin, Xinchao Zhang et al. · Cell Discovery · 2023 · 22 citations · Full text

FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation

Tongguan Tian, Xiao Xie, Wanwan Yi et al. · Cell Reports · 2023 · 18 citations · Full text