Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

Shu Zhu, Siyuan Ding, Penghua Wang, +22

Nature

InflammationMucosal ImmunologyImmunologyGastroenterologyPathology +4

Nlrp6 regulates intestinal antiviral innate immunity

Penghua Wang, Shu Zhu, Long Yang, +12

Science

InflammationMolecular VirologyNlrp6 FunctionsMucosal ImmunologyPathogenesis +13

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity

Nan Ring, Dietmar Herndler‐Brandstetter, Kipp Weiskopf, +11

Proceedings of the National Academy of Sciences

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

Wen Pan, Shu Zhu, Dai Dai, +21

Nature Communications

Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions

Eleanna Kaffe, Manolis Roulis, Jun Zhao, +11

Cell

HepatologyMouse LiverLiver PhysiologyPhysiologyEndothelial Control +11

Human neutrophil development and functionality are enabled in a humanized mouse model

Yunjiang Zheng, Esen Sefik, John Astle, +9

Proceedings of the National Academy of Sciences

Innate Immune SystemImmunologyInnate ImmunityImmune SystemImmunotherapy +19

Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment

Michael Chiorazzi, Jan Martínek, Bradley A. Krasnick, +31

Journal for ImmunoTherapy of Cancer

Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes

Xingxing Ren, Decai Wang, Guorong Zhang, +10

Science Advances

Transcriptional RegulationImmunogeneticsSystems BiologyGeneticsImmunology +10

Proinflammatory effects and molecular mechanisms of interleukin-17 in intestinal epithelial cell line HT-29

Yilin Wang, Meng Fang, Xiaoming Wang, +4

World Journal of Gastroenterology