Jenna M. Lentini

TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival

Joshua M. Dewe, Benjamin L. Fuller, Jenna M. Lentini et al. · Molecular and Cellular Biology · 2017 · 123 citations · Full text

Life Sciences, Genetics, Cellular Metabolism +3

DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification

Jenna M. Lentini, Hessa S. Alsaif, Eissa Faqeih et al. · Nature Communications · 2020 · 79 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +11

An intellectual disability‐associated missense variant in TRMT1 impairs tRNA modification and reconstitution of enzymatic activity

Kejia Zhang, Jenna M. Lentini, Christopher T. Prevost et al. · Human Mutation · 2020 · 50 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

THUMPD1 bi-allelic variants cause loss of tRNA acetylation and a syndromic neurodevelopmental disorder

Martin Broly, Bogdan Polevoda, Kamel Awayda et al. · The American Journal of Human Genetics · 2022 · 47 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Monitoring the 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) modification in eukaryotic tRNAs via the γ-toxin endonuclease

Jenna M. Lentini, Jillian Ramos, Dragony Fu · RNA · 2018 · 32 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12