Kinuko Mitani

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

Motoshi Ichikawa, Takashi Asai, Go Yamamoto et al. · Nature Medicine · 2004 · 575 citations

Hematological Malignancy, Developmental Biology, Medicine +12

The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3

Mineo Kurokawa, Kinuko Mitani, Kenji Irie et al. · Nature · 1998 · 378 citations

Signal Transduction, Signaling Pathway, Immunology +3

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

Kinuko Mitani, Seishi Ogawa, Tetsuhiro Tanaka et al. · The EMBO Journal · 1994 · 332 citations · Full text

Hematological Malignancy, Immunology, Aml1-evi-1 Fusion Gene +7

Alternative splicing and genomic structure of the<i>AML1</i>gene involved in acute myeloid leukemia

Hiroyuki Miyoshi, Miki Ohira, Kimiko Shimizu et al. · Nucleic Acids Research · 1995 · 269 citations · Full text

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

Tomoyuki Tanaka, Kozo Tanaka, Seishi Ogawa et al. · The EMBO Journal · 1995 · 231 citations · Full text

Hematological Malignancy, Transcriptional Regulation, Mixed-phenotype Acute Leukemia +8