Simulation model for overloaded monoclonal antibody variants separations in ion-exchange chromatography

Bertrand Guélat, Guido Ströhlein, Marco Lattuada, +3

Journal of Chromatography A

Simulation ModelImmunohematologyIon-exchange ChromatographyEngineeringBioanalysis +10

Electrostatic model for protein adsorption in ion-exchange chromatography and application to monoclonal antibodies, lysozyme and chymotrypsinogen A

Bertrand Guélat, Guido Ströhlein, Marco Lattuada, +1

Journal of Chromatography A

Protein ChemistryEngineeringIon ExchangeBiochemistryBioanalysis +9

Protein adsorption on ion exchange resins and monoclonal antibody charge variant modulation

Bertrand Guélat, Rushd Khalaf, Marco Lattuada, +2

Journal of Chromatography A

Ion ExchangeBiochemistryNatural SciencesIon Exchange ResinsBioanalysis +10

Combined Yamamoto approach for simultaneous estimation of adsorption isotherm and kinetic parameters in ion-exchange chromatography

Matthias Rüdt, F. Gillet, Stefanie Heege, +2

Journal of Chromatography A

Chemical EngineeringEngineeringIon ExchangeGas ChromatographyKinetic Parameters +9

Application of Transition-Metal Catalysis, Biocatalysis, and Flow Chemistry as State-of-the-Art Technologies in the Synthesis of LCZ696

Xingxian Gu, Jibin Zhao, Like Chen, +40

The Journal of Organic Chemistry

Heart FailureEngineeringOrganic ChemistryState-of-the-art TechnologiesChemistry +15

Model-based prediction of monoclonal antibody retention in ion-exchange chromatography

Bertrand Guélat, Lydia Delegrange, Pascal Valax, +1

Journal of Chromatography A

BioanalysisImmunologyAntibody ScreeningImmunochemistryAnalytical Chemistry +5

Reaction Calorimetry in Continuous Flow Mode: A New Approach for the Thermal Characterization of High Energetic and Fast Reactions

Frederik B. Mortzfeld, Jutta Polenk, Bertrand Guélat, +3

Organic Process Research & Development

Flow ModeEngineeringDifferential Scanning CalorimetryExperimental ThermodynamicsFast Reactions +15

Fouling of Flow Reactors in Organolithium Mediated Transformations: Experience on Scale-up and Proposed Solution

Paolo Filipponi, Francesco Venturoni, Roger Suremann, +10

CHIMIA International Journal for Chemistry

FiltrationEngineeringPipe FoulingFoulingMineral Processing +17

The scale-up of continuous biphasic liquid/liquid reactions under super-heating conditions: methodology and reactor design

Francesca Mandrelli, Alessia Buco, Lorenzo Piccioni, +5

Green Chemistry

EngineeringLiquid Metal CoolingReactor DesignLiquid-liquid FlowExperimental Thermodynamics +15

A two level hierarchical model of protein retention in ion exchange chromatography

Matteo Salvalaglio, Matteo Paloni, Bertrand Guélat, +2

Journal of Chromatography A

Protein ChemistryIon ExchangeBiochemistryLevel Hierarchical ModelProtein Folding +11