Troy A. A. Harkness

Elevated Histone Expression Promotes Life Span Extension

Jason Feser, David M. Truong, Chandrima Das et al. · Molecular Cell · 2010 · 416 citations · Full text

Histone Modifications, Chromatin, Lifespan Extension +9

Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene regulation.

Xuefeng B. Ling, Troy A. A. Harkness, Michael C. Schultz et al. · Genes & Development · 1996 · 131 citations · Full text

Histone Amino Termini, H4 Amino Termini, Amino Termini +21

Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells

Alexander A. Goldberg, Adam Beach, Gerald F. Davies et al. · Oncotarget · 2011 · 110 citations · Full text

Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan

Zheng Hu, Bo Xia, Spike D. L. Postnikoff et al. · eLife · 2018 · 88 citations · Full text

Molecular Biology, Translation Efficiency, Cell Autophagy +19

Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro transposition characteristics of mini-Mu plasmids carrying terminal base pair mutations.

Michael G. Surette, Troy A. A. Harkness, George Chaconas · Journal of Biological Chemistry · 1991 · 72 citations · Full text

Genome Instability, Vitro Transposition Reaction, Natural Sciences +15