HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies

Mariesa J. Slaughter, Erin K. Shanle, Abid Khan, +9

Cell Reports

Binding Optimization through Coordination Chemistry: CXCR4 Chemokine Receptor Antagonists from Ultrarigid Metal Complexes

Abid Khan, Gary Nicholson, John Greenman, +10

Journal of the American Chemical Society

<i>SETD2</i> Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma

Yun-Chen Chiang, In-Young Park, Esteban Terzo, +18

Cancer Research

Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization

Yating Wang, Abid Khan, Anna B. Marks, +8

Nucleic Acids Research

Epigenetic ChangeGeneticsDna MethylationLate-firing OriginsMolecular Biology +16

The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin

Sumanprava Giri, Vasudha Aggarwal, Julien Pontis, +8

eLife

Histone ModificationsHistone H3Prerc Protein OrcaGeneticsEpigenetic Change +18

ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins

Aparna Anantharaman, Vidisha Tripathi, Abid Khan, +13

Nucleic Acids Research

Rna SplicingMolecular BiologyGene TranscriptionTranscriptional RegulationRna Binding Proteins +16

BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase

Abid Khan, Sumanprava Giri, Yating Wang, +8

Proceedings of the National Academy of Sciences

Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding

Abid Khan, J.D. Silversides, Leigh A. Madden, +2

Chemical Communications

Chemokine BiologyMedicineMetalloproteinImmunologyReceptor (Biochemistry) +9

PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes

Deepak Kumar Singh, Omid Gholamalamdari, Mahdieh Jadaliha, +18

Carcinogenesis

Radiation OncologyCell RegulationCell Cycle GenesMedicineNatural Sciences +11

Probing key coordination interactions: configurationally restricted metal activated CXCR4 antagonists

Graeme McRobbie, Gina C. Valks, Christopher J. Empson, +8

Dalton Transactions