Amin A. Nomeir

Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor

David Parry, Timothy J. Guzi, Nicole R. Davis et al. · Molecular Cancer Therapeutics · 2010 · 553 citations · Full text

Pharmacotherapy, Cancer Biology, Tumor Biology +16

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

Sch 66336, Chemoprevention Strategy, Farnesyl Protein Transferase +15

The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America

Scott Grimm, Heidi J. Einolf, Steven D. Hall et al. · Drug Metabolism and Disposition · 2009 · 304 citations

Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity

Craig A. Coburn, Peter T. Meinke, Wei Chang et al. · ChemMedChem · 2013 · 196 citations · Full text

Hcv Ns5a Inhibitor, Broad Genotype Activity, Vitro Potency Profiles +17

Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases

Kamil Paruch, Michael P. Dwyer, Carmen Álvarez et al. · ACS Medicinal Chemistry Letters · 2010 · 174 citations · Full text

Drug Target, Pathology, Chemical Biology +21